• Goujon I
  • PV 241
  • Décembre 2003
  • : Chien, chat

(1) BSAVA mission statement
The British Small Animal Veterinary Association exists to promote high scientific and educational standards of small animal medicine and surgery in practice, teaching and research.
Provides a forum for the discussion of issues of importance to veterinary surgeons in small animal practice and submits evidence on their behalf to the British Veterinary Association and the Royal College of Veterinary Surgeons as well as to government departments.

(2) The Royal College of Veterinary Surgeons (RCVS) is the regulatory body for veterinary surgeons in the United Kingdom and ensures that standards within the veterinary profession are maintained, safeguarding the health and welfare of animals and the interests of the public. Click here to find out more about the RCVS or to contact us.

1. The purpose of these Guidelines is to safeguard the position of source and recipient animals involved in transplant procedures. It is the involvement of source animals which makes transplant procedures uniquely different in ethical terms from any other procedures.
2. These Guidelines are intended to apply in the first instance only to kidney transplants in cats, as this is the only procedure likely to be seriously contemplated in the United Kingdom in the immediate future, and will be reviewed regularly.
3. The College takes the view that the transplantation of kidneys in cats should be regarded as ethically acceptable in the United Kingdom, but only if carried out in accordance with the Guidelines set out below. In devising the Guidelines below, it has deliberately set high standards which must be attained before transplants can be undertaken in the United Kingdom.
4. The College accepts that only a few Members may choose to carry out this procedure.
5. The Home Office has accepted that kidney transplants in cats can be ‘recognised veterinary practice' and, as such, exempt from the need for a Home Office licence under the Animals (Scientific Procedures) Act 1986. This is supported by Counsel's opinion sought jointly by the RCVS, the British Small Animal Veterinary Association and the Royal Society for the Prevention of Cruelty to Animals (RSPCA), (the "Legal Opinion").
6. The RSPCA has indicated that the removal of a major organ from a living source animal might constitute an offence under the Protection of Animals Act 1911 and this possibility is supported by the Legal Opinion. However, the RSPCA has indicated that the degree to which this RCVS advice is followed will "influence any decision the RSPCA might take in considering the likelihood of a prosecution relating to organ transplantation between animals."

Part A: Ethical sourcing
7. All source animals must be treated with compassion and respect.
8. Organs for transplantation should not be commercially produced for the purpose; source animals should not be bred or bought for the purpose of transplantation.
9. The responsibility to provide a suitable source animal should normally be for the transplantation centre.

Part B: Balancing the interests of the source and recipient animals
10. Transplantation centres must give equal consideration to the interests of the source and recipient animals in deciding whether it is appropriate to proceed.
11. Source animals should be assessed for adequate renal function. In every case there must be the necessary compatibility between the source animal and the potential recipient animal. The level of distress caused to the source animal should be kept to a minimum. Source animals should be used on only one occasion.
12. In the event that the source animal is to be adopted or is already owned, then the owner or future owner needs to be fully informed of the procedure and any possible long term implications to the source animal. The owner of the recipient animal must be informed of the potential outcomes for the recipient animal. Owners must give informed consent to all procedures, which should be confirmed in writing.
13. Source animals should only be euthanased when there is no reasonable alternative.

Part C: Transplant centres
14. Centres intending to carry out transplantation procedures must meet the following requirements:
15. To safeguard both the source and recipient animals, there must be a suitably qualified team of veterinary surgeons to remove and implant the organ and to provide the necessary post-operative support, both to the source and recipient animals. The team should include veterinary surgeons with Diplomate or Board Certified Level qualifications in Medicine, Soft Tissue Surgery and Anaesthesia and qualifications or experience in microvascular surgery and critical care. Ideally, at least one member of the team should have first hand experience of transplant surgery at another centre over a period of time.
16. To safeguard the ongoing care of the recipient and source animals, the centre must ensure satisfactory arrangements for long-term care, as determined by the group specified in paragraph 15. In particular, before carrying out transplantation procedures the centre must a) provide the recipient's primary practice with aftercare guidelines, and b) ensure that the veterinary surgeon(s) from the primary practice are willing and able to undertake this aftercare.
17. Approved centres will be expected to be up to date with current developments that significantly improve outcomes, keep appropriate records of the transplantations carried out and undertake regular audit of clinical outcomes.
18. The centre must have an Ethics Committee to ensure that all procedures are subject to rigorous and critical review. This Committee should include lay representation and must represent the health and welfare interests of both source and recipient animals and the views of staff involved.

19. Centres seeking formal confirmation that they meet the requirements above may ask RCVS to appoint an Inspector for the purpose. The costs of the inspection are to be borne by the Centre seeking approval.

27 February 2003

Sites d'universités qui proposent des transplantations rénales aux Etats-Unis :
a - http://www.vet.cornell.edu/hospital/kidneycare/
b - http://www.vmth.ucdavis.edu/vmth/clientinfo/info/sasurg/felrenaltransplant.html
c - http://www.vet.upenn.edu/departments/csp/surgery/programs/
d - http://www.marvistavet.com/html/body_kidney_transplants_in_cats.html